Dirty Secrets of Menopause: Gut Health, Immunity & Inflammation | Dr. Charles Akle

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This week, I sit down with Charles Akle, MD, an innovator in immunology who has devoted his life to helping others discover wellness by addressing the root causes of chronic inflammation. Dr. Akle now serves as Chief Medical Officer of Immy, a supplement designed to combat chronic illnesses through inflammation and immune support.

We dive deep into the silent enemy—chronic inflammation—and how it’s tied to everything from stress and cancer to the very process of aging and menopause. Dr. Akle discusses the importance of farming your microbiome for resilience and longevity.

You’ll learn why your gut is your biggest immune organ, why getting "dirty" is vital (the "Old Friends Hypothesis"), and the red flags your body is giving you when inflammation is in control.

We also discuss the groundbreaking power of Fecal Microbiome Transplants (FMT), the essential role of the immune system in your menopausal transition, and the non-negotiable importance of a holistic approach that includes diet, exercise, sleep, and the people who love you.

Ready to empower your immune system? Shop Immy and use my code MISSY10 for 10% OFF your purchase: https://immy.sjv.io/raKOGG

Immy Social Media Info:

Instagram: https://www.instagram.com/immyhealth
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Website: https://www.immy.co/

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Timestamps

00:00 Intro

00:52 Dr. Akle’s Journey: From Oncology to Immunology

05:53 Why Your Gut is Your Biggest Immune Organ

08:51 The Importance of Microbial Diversity

12:31 The Cancer-Immunology Connection

16:42 Immy: The “Conductor” of Your Microbiome

19:54 How to Farm Your Microbiome

26:47 Coping with Post-Viral Illness

30:17 The Connection Between Chronic Inflammation and Cancer Risk

33:59 The Groundbreaking Power of FMT

37:22 Red Flags of Chronic Inflammation

42:28 Why Your Supplement Source Matters

49:48 Menopause, Hormones, and the Gut Shift

01:01:11 Rapid-fire Questions